Health care, medicine and manufacturing dominate the Fortune 500 map in Indiana. Elevance Health brings the largest revenue total, Eli Lilly carries the biggest global spotlight, and Cummins remains the best-known industrial name outside Indianapolis.
The 2026 list also reaches beyond the capital. Fort Wayne appears through Steel Dynamics, Elkhart through THOR Industries, Evansville through Berry Global, and Warsaw through Zimmer Biomet. Indianapolis still leads by company count, with Elevance Health, Eli Lilly and Corteva all tied to the city.
The table below uses the latest Fortune 500 ranking and current company information.
| Indiana Rank | Fortune 500 Rank | Company | Headquarters | Main Business | Revenue |
|---|---|---|---|---|---|
| 1 | 17 | Elevance Health | Indianapolis | Health insurance and managed care | $199.1 billion |
| 2 | 65 | Eli Lilly and Company | Indianapolis | Pharmaceuticals | $65.2 billion |
| 3 | 134 | Cummins | Columbus | Engines, power systems and industrial equipment | $33.7 billion |
| 4 | 238 | Steel Dynamics | Fort Wayne | Steel production and metals recycling | $18.2 billion |
| 5 | 248 | Corteva | Indianapolis | Seeds, crop protection and agricultural science | $17.4 billion |
| 6 | 351 | Berry Global | Evansville | Packaging and containers | $12.3 billion |
| 7 | 416 | THOR Industries | Elkhart | Recreational vehicles | $9.6 billion |
| 8 | 462 | Zimmer Biomet | Warsaw | Orthopedic medical devices | $8.2 billion |
1. Elevance Health Leads By Revenue
| Headquarters | Indianapolis, Indiana |
| 2026 Fortune 500 Rank | No. 17 |
| Revenue | $199.1 billion |
| Main Business | Health insurance, managed care, government health programs and care services |
| Stock Ticker | ELV |
| Recent Note | The company raised full-year adjusted earnings guidance after first-quarter 2026 results. |
Elevance Health is the largest Fortune 500 company headquartered in Indiana. The Indianapolis-based insurer ranks No. 17 nationally, with $199.1 billion in revenue.
The company runs health plans, employer coverage, government health programs and care services. Its business reaches far beyond Indiana, but the headquarters keeps Indianapolis connected to one of the largest health insurance operations in the United States.
Elevance entered 2026 with higher earnings guidance after first-quarter results, according to its latest earnings release. The company matters locally because health insurance affects employers, hospitals, public programs and household costs throughout the state.
2. Eli Lilly Puts Indianapolis In The Global Drug Market
| Headquarters | Indianapolis, Indiana |
| 2026 Fortune 500 Rank | No. 65 |
| Revenue | $65.2 billion |
| Main Business | Prescription medicines, diabetes care, obesity treatment, oncology, immunology and neuroscience |
| Stock Ticker | LLY |
| Recent Note | Lilly announced another $4.5 billion in Indiana manufacturing investment in May 2026. |
Eli Lilly ranks No. 65 on the 2026 Fortune 500, with $65.2 billion in revenue. No Indiana company has a larger global profile right now.
Demand for Lilly diabetes and weight-loss drugs has turned the company into one of the most watched names in medicine. Mounjaro and Zepbound have pushed Lilly to expand factories, add supply capacity and spend heavily on research.
Indiana is central to that expansion. In May 2026, Lilly announced another $4.5 billion in Indiana manufacturing investment, bringing its state manufacturing commitments since 2020 to more than $21 billion, according to the company announcement.
That money reaches construction firms, suppliers, engineers, lab workers and the wider Indianapolis region. Lilly has become both an Indiana employer and a global health care force.
3. Cummins Keeps Columbus Connected To Global Industry
| Headquarters | Columbus, Indiana |
| 2026 Fortune 500 Rank | No. 134 |
| Revenue | $33.7 billion |
| Main Business | Engines, generators, power systems, components and distribution services |
| Stock Ticker | CMI |
| Recent Note | Power Systems demand and data center backup power supported first-quarter 2026 results. |
Cummins ranks No. 134 in the 2026 Fortune 500, with $33.7 billion in revenue. The company is based in Columbus and remains one of the most important industrial manufacturers in Indiana.
Cummins builds engines, generators, power systems, components and distribution services. Its customers include trucking, construction, mining, rail, marine, data center and power generation markets.
The company is also moving beyond diesel. Accelera, its clean-power business, works on batteries, fuel cells, electric powertrains and hydrogen systems. Traditional engines and power systems still drive much of the revenue, but the company is spending on lower-emission technology at the same time.
Cummins reported better first-quarter results in 2026, helped by power systems demand and data center backup power, according to a company SEC filing.
4. Steel Dynamics Makes Fort Wayne A Major Steel Center
| Headquarters | Fort Wayne, Indiana |
| 2026 Fortune 500 Rank | No. 238 |
| Revenue | $18.2 billion |
| Main Business | Steel production, metals recycling, fabrication and aluminum operations |
| Stock Ticker | STLD |
| Recent Note | The company remains one of the largest U.S. steel producers and metals recyclers. |
Steel Dynamics ranks No. 238 on the 2026 Fortune 500, with $18.2 billion in revenue. The Fort Wayne company is one of the largest steel producers and metals recyclers in the country.
The company makes flat roll steel, structural steel, rail, engineered bar products and fabricated steel. Its recycling operations also give it a large role in scrap processing and lower-waste metal production.
Steel Dynamics is important for Indiana because it connects the state to construction, autos, machinery, packaging and broader manufacturing supply chains. The company also shows how Fort Wayne fits into the national industrial economy.
5. Corteva Adds Agriculture Science To The Indianapolis List
| Headquarters | Indianapolis, Indiana |
| 2026 Fortune 500 Rank | No. 248 |
| Revenue | $17.4 billion |
| Main Business | Seeds, crop protection products and agricultural science |
| Stock Ticker | CTVA |
| Recent Note | Corteva said its future crop protection company, New Corteva, will be headquartered in Indianapolis after its planned split. |
Corteva ranks No. 248 in the 2026 Fortune 500, with $17.4 billion in revenue. The company is based in Indianapolis and works in seeds, crop protection and agricultural science.
Corteva sells products used by farmers to manage weeds, insects, disease pressure and crop productivity. Its work ties Indianapolis to agriculture, research and the wider Midwest farm economy.
In May 2026, Corteva announced that its future crop protection company, New Corteva, will be headquartered in Indianapolis after a planned separation into two public companies. The seed and genetics company, Vylor, will be based in Johnston, Iowa, according to the company announcement.
That decision keeps a major agriculture science headquarters in Indiana and gives Indianapolis another large company tied to research, production and global markets.
6. Berry Global Keeps Evansville On The List, With A Note
| Headquarters Listed In 2026 Data | Evansville, Indiana |
| 2026 Fortune 500 Rank | No. 351 |
| Revenue | $12.3 billion |
| Main Business | Packaging, containers, films and plastic products for consumer, health care and industrial markets |
| Stock Ticker | Formerly BERY before the Amcor combination |
| Recent Note | Berry completed its combination with Amcor on April 30, 2025, so it should be described with that ownership note. |
Berry Global ranks No. 351 in the 2026 Fortune 500 data, with $12.3 billion in revenue and Evansville listed as headquarters. The company makes packaging and container products used in food, health care, personal care, consumer goods and industrial markets.
Berry should stay in the Indiana table because current ranking data still lists the company with Evansville. The company also has a long operating history in the state.
A note is needed because Berry completed its combination with Amcor on April 30, 2025. Amcor said the deal created a larger global consumer and health care packaging company, according to the transaction announcement.
For readers, the clean explanation is simple: Berry appears in the latest Fortune 500 data with Evansville listed, but the company now sits under Amcor.
7. THOR Industries Keeps Elkhart At The Center Of RV Manufacturing
| Headquarters | Elkhart, Indiana |
| 2026 Fortune 500 Rank | No. 416 |
| Revenue | $9.6 billion |
| Main Business | Recreational vehicles, including towable and motorized RVs |
| Stock Ticker | THO |
| Recent Note | THOR remains tied to RV demand, consumer financing conditions, dealer inventory and travel spending. |
THOR Industries ranks No. 416 on the 2026 Fortune 500, with $9.6 billion in revenue. The company is headquartered in Elkhart, one of the best-known RV manufacturing centers in the country.
THOR owns major RV brands and sells towable and motorized recreational vehicles in North America and Europe. Its business is closely tied to consumer confidence, interest rates, dealer inventory and travel spending.
That makes THOR a useful signal for northern Indiana. When RV demand rises, factories, suppliers and local services feel the lift. When demand slows, Elkhart tends to feel that quickly.
8. Zimmer Biomet Keeps Warsaw In The Medical Device Business
View this post on Instagram
| Headquarters | Warsaw, Indiana |
| 2026 Fortune 500 Rank | No. 462 |
| Revenue | $8.2 billion |
| Main Business | Orthopedic implants, surgical tools, joint replacement products and digital surgery technology |
| Stock Ticker | ZBH |
| Recent Note | The company reported first-quarter 2026 net sales of $2.087 billion, up 9.3% from the prior-year period. |
Zimmer Biomet ranks No. 462 in the 2026 Fortune 500, with $8.2 billion in revenue. The company is headquartered in Warsaw, a city closely tied to orthopedic medical device manufacturing.
Zimmer Biomet makes products for joint replacement, sports medicine, trauma, spine, dental and surgical uses. Hospitals and surgeons use its implants, instruments and digital surgery tools in the United States and abroad.
In April 2026, Zimmer Biomet reported first-quarter net sales of $2.087 billion, up 9.3% on a reported basis from the prior-year period, according to the company earnings release.
Zimmer Biomet gives Indiana a specialized manufacturing cluster outside the largest cities. Warsaw may not have the size of Indianapolis, but it carries a global role in orthopedic devices.
The Bottom Line
The 2026 Fortune 500 list shows a state economy split between health care, science and manufacturing.
Elevance and Lilly dominate the revenue picture from Indianapolis. Cummins, Steel Dynamics and THOR show the older industrial base is still large. Corteva adds agriculture science, Berry adds packaging, and Zimmer Biomet keeps medical devices in the mix.
The spread also shows why Indiana business is not only an Indianapolis story. Columbus, Fort Wayne, Evansville, Elkhart and Warsaw all appear on the Fortune 500 map.
That same wider pattern shows up in our guide to Indiana biggest cities, where several mid-sized communities carry jobs and companies that matter statewide.
Readers can also compare the corporate picture with current Indiana unemployment data, because the largest companies help explain where parts of the state labor market are strongest.
